Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Ana on Hotels.com. These Santa Ana hotels consistently deliver on quality, location and traveler experience. Last updated on .
Hotels in Santa Ana

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1. Holiday Inn Express & Suites Santa Ana - Orange County by IHG
Holiday Inn Express & Suites Santa Ana - Orange County by IHGLyon Street
8.8 out of 10, Excellent, (1,237 reviews)
The price is ¥17,489
¥19,796 total
includes taxes & fees
Nov 30 - Dec 1

2. Best Western Plus Orange County Airport North
Best Western Plus Orange County Airport NorthSanta Ana
8.6 out of 10, Excellent, (1,956 reviews)
The price is ¥17,141
¥19,369 total
includes taxes & fees
Nov 16 - Nov 17

3. Comfort Inn & Suites Orange County John Wayne Airport
Comfort Inn & Suites Orange County John Wayne AirportSanta Ana
8.0 out of 10, Very good, (1,254 reviews)
The price is ¥14,645
¥16,576 total
includes taxes & fees
Nov 29 - Nov 30

4. Holiday Inn Santa Ana-Orange Co. Arpt by IHG
Holiday Inn Santa Ana-Orange Co. Arpt by IHGSanta Ana
8.8 out of 10, Excellent, (1,630 reviews)
The price is ¥16,544
¥18,726 total
includes taxes & fees
Nov 25 - Nov 26

5. La Quinta Inn & Suites by Wyndham Orange County Airport
La Quinta Inn & Suites by Wyndham Orange County AirportSanta Ana
7.8 out of 10, Good, (2,158 reviews)
The price is ¥14,004
¥15,824 total
includes taxes & fees
Nov 29 - Nov 30

6. MainStay Suites John Wayne Airport by Choice Hotels
MainStay Suites John Wayne Airport by Choice HotelsSanta Ana
8.0 out of 10, Very good, (2,319 reviews)
The price is ¥14,598
¥16,524 total
includes taxes & fees
Nov 22 - Nov 23

7. Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Hotel Zessa Orange County Airport, a DoubleTree by HiltonSanta Ana
9.0 out of 10, Wonderful, (835 reviews)
The price is ¥17,410
¥19,673 total
includes taxes & fees
Nov 27 - Nov 28

8. Courtyard by Marriott Santa Ana Orange County
Courtyard by Marriott Santa Ana Orange CountySanta Ana
8.6 out of 10, Excellent, (1,005 reviews)
The price is ¥18,293
¥20,707 total
includes taxes & fees
Nov 8 - Nov 9

9. Embassy Suites by Hilton Santa Ana Orange County Airport
Embassy Suites by Hilton Santa Ana Orange County AirportSanta Ana
6.4 out of 10, Good, (2,121 reviews)
The price is ¥17,946
¥20,314 total
includes taxes & fees
Nov 8 - Nov 9

10. City Express by Marriott Santa Ana/Orange County Airport
City Express by Marriott Santa Ana/Orange County AirportSanta Ana
7.2 out of 10, Good, (1,007 reviews)
The price is ¥17,332
¥19,619 total
includes taxes & fees
Nov 22 - Nov 23

11. voco Orange County - Airport by IHG
voco Orange County - Airport by IHGSanta Ana
7.6 out of 10, Good, (1,004 reviews)
The price is ¥17,962
¥20,332 total
includes taxes & fees
Nov 23 - Nov 24

12. Motel 6 Santa Ana, CA
Motel 6 Santa Ana, CASanta Ana
7.4 out of 10, Good, (1,001 reviews)
The price is ¥12,605
¥14,717 total
includes taxes & fees
Nov 8 - Nov 9

13. Ayres Hotel Costa Mesa/Newport Beach
Ayres Hotel Costa Mesa/Newport BeachSanta Ana
9.0 out of 10, Wonderful, (3,455 reviews)
The price is ¥20,309
¥22,582 total
includes taxes & fees
Dec 4 - Dec 5

14. Courtyard by Marriott Costa Mesa South Coast Metro
Courtyard by Marriott Costa Mesa South Coast MetroSanta Ana
8.6 out of 10, Excellent, (1,001 reviews)
The price is ¥22,303
¥25,317 total
includes taxes & fees
Nov 8 - Nov 9

15. Studio 6 Suites Santa Ana, Ca
Studio 6 Suites Santa Ana, CaSanta Ana
8.2 out of 10, Very good, (99 reviews)
The price is ¥15,754
¥17,487 total
includes taxes & fees
Nov 4 - Nov 5

16. Sonesta Simply Suites Orange County Airport
Sonesta Simply Suites Orange County AirportSanta Ana
7.2 out of 10, Good, (1,001 reviews)
The price is ¥16,386
¥18,549 total
includes taxes & fees
Nov 9 - Nov 10

17. Santa Ana Travel Inn
Santa Ana Travel InnSanta Ana
5.8 out of 10, (160 reviews)
The price is ¥9,368
¥10,398 total
includes taxes & fees
Nov 4 - Nov 5

18. Red Roof Inn Santa Ana
Red Roof Inn Santa AnaSanta Ana
6.8 out of 10, Good, (1,001 reviews)
The price is ¥15,754
¥17,833 total
includes taxes & fees
Nov 4 - Nov 5

19. Rodeway Inn Santa Ana - Garden Grove
Rodeway Inn Santa Ana - Garden GroveSanta Ana
7.4 out of 10, Good, (43 reviews)
The price is ¥17,711
¥20,132 total
includes taxes & fees
Dec 2 - Dec 3

20. Motel 6 Irvine - Orange County Airport
Motel 6 Irvine - Orange County AirportSanta Ana
7.6 out of 10, Good, (1,938 reviews)
The price is ¥10,454
¥11,837 total
includes taxes & fees
Nov 16 - Nov 17
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Nov 3 - Nov 4

8.6 out of 10, Excellent, (1,956 reviews)
We have 2 left at
The price is ¥17,157
per night
¥19,387 total
includes taxes & fees
Showing deals for:Nov 13 - Nov 15

8.6 out of 10, Excellent, (1,956 reviews)
The price is ¥19,828
per night
¥44,812 total
includes taxes & fees
Check out pet-friendly hotels in Santa Ana

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Hotel Zessa Orange County Airport, a DoubleTree by HiltonSanta Ana
9.0 out of 10, Wonderful, (835)
The price is ¥17,410
¥19,673 total
includes taxes & fees
Nov 27 - Nov 28
You may also like hotels with pools in Santa Ana

Holiday Inn Express & Suites Santa Ana - Orange County by IHG
Holiday Inn Express & Suites Santa Ana - Orange County by IHGLyon Street
8.8 out of 10, Excellent, (1237)
The price is ¥17,489
¥19,796 total
includes taxes & fees
Nov 30 - Dec 1
You can also stay at hotels with a hot tub in Santa Ana

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Hotel Zessa Orange County Airport, a DoubleTree by HiltonSanta Ana
9.0 out of 10, Wonderful, (835)
The price is ¥17,410
¥19,673 total
includes taxes & fees
Nov 27 - Nov 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Santa Ana
Pet friendly
Top neighborhoods in Santa Ana

Downtown Santa Ana
Downtown Santa Ana blends Latino heritage with artistic flair in its walkable streets. The ornate Old Orange County Courthouse stands amid colorful murals and bustling Hispanic markets. Artists Village buzzes with galleries and studios hosting a popular monthly Art Walk, while authentic taquerias serve up mouthwatering Mexican cuisine alongside craft breweries. The neighborhood is easily explored on foot with wide sidewalks and historic architecture at every turn. Public transportation connects through the Santa Ana Regional Transportation Center, making day trips simple. Accommodation options range from business hotels to boutique properties, all within reach of this cultural hotspot.

Artists Village
Artists Village packs a punch with its revitalized brick warehouses now home to working studios where you can watch painters and sculptors in action. The monthly First Saturday Art Walk transforms streets into buzzing outdoor galleries with creative energy spilling from every corner. Peek through floor-to-ceiling windows to glimpse artists at work or catch a show at the vintage-marquee theater. Fuel your creative journey at artisan cafes and craft breweries housed in industrial-chic spaces with mid-range prices. Boutique hotels in converted buildings offer artistic lodging options, while the compact, walkable district makes exploration easy even without a car. Limited public transit connects to the wider Santa Ana area.

North Tustin
North Tustin offers a peaceful retreat with tree-lined streets and spacious homes just minutes from Orange County attractions. Stroll through this upscale residential neighborhood and soak up the suburban California dream. Nearby Peters Canyon Regional Park delivers scenic hiking trails with mountain views that most tourists never discover. Getting around requires a car, but that's perfect for quick trips to Disneyland or Newport Beach. Vacation rentals showcase luxury living with private pools and manicured gardens. The quiet evenings and morning birdsong provide a welcome break from touristy areas.

Riverview West
Riverview West offers a peaceful escape from Orange County's tourist rush. This family-friendly Santa Ana neighborhood borders Santiago Creek, where walking paths invite you to stretch your legs. While there aren't major attractions within its boundaries, you're just a short drive from Disneyland and Knott's Berry Farm. The area's tree-lined streets and parks create a genuine slice of suburban SoCal life. Local taco shops and family restaurants serve up authentic Mexican cuisine at wallet-friendly prices. Most visitors opt to rent cars since public transit is limited, though ride-sharing services are readily available. Budget motels and vacation rentals make this a smart base for exploring Orange County without coastal price tags.

Park Santiago
Santa Ana's Park Santiago neighborhood is home to attractions such as Discovery Science Center and Santiago Park.
Top landmarks in Santa Ana
Learn more about Santa Ana
Discover Orange County's cultural heart at the Bowers Museum, showcasing art and artifacts from around the globe. Unleash your inner scientist at Discovery Science Center, then catch a live show at The Observatory's intimate music venue.

Check out reviews of Santa Ana hotels guests love

The Queen Mary
10/10 Excellent
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